Jonathan Bloom is a most curious mathematician and teacher. Jon grew up in Michigan and studied math at Harvard (BA) and Columbia (PhD). As an MIT C.L.E. Moore Instructor and a National Science Foundation (NSF) postdoctoral fellow, he proved theorems about 3- and 4-dimensional shapes. Jon’s experience redeveloping 18.05 (Probability and Statistics) kicked off a quest into computational biology and machine learning. As an Institute Scientist at the Broad Institute, he developed open-source software to learn from massive genomic datasets and organized the community Models, Inference & Algorithms. At the biotech startup Cellarity, he led a team of computational scientists to design single-cell experiments and algorithms to advance drug discovery. Jon returned to MIT in 2023 to geek out at ESG, build on 18.05, and ponder topology. He bikes in from Arlington, where he plays soccer and Taylor Swift with his daughters.